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Aging accelerates the progression of PD through various mechanisms

More recently, immunoprecipitation-based RT-QUiC, detected pathogenic alpha-synuclein in serum, with high sensitivity and specificity in discriminating PD as well as DLB from controls 105

66 In the context of ARDS, abnormalities in the metabolism of amino acid can influence the development of the disease and aggravate the inflammatory response and ROS generation (Figure 3)

Histone-modifying enzymes contribute to this regulatory network by controlling chromatin accessibility, thereby affecting the expression of genes critical for endocytosis, endosome formation and recycling process (Wang H